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Researcher Highlight – Dr Scott Echols. U of Utah Research

Researcher Highlight – Dr Scott Echols. U of Utah Research

Dr Scott Echols, founder of Scarlet Imaging and creator of BriteVu, was the ‘Researcher Highlight’ subject at the U of Utah (Nov 2015). Dr Echols has been conducting and involved with a number of research projects at the U of Utah.  His work has lead to the creation of BriteVu and other discoveries that are being used by researchers all over the world. Association of Avian Veterinarians.  Newsletter.  November, 2015. Login required: https://aav.site-ym.com/global_engine/download.asp?fileid=E2446ED6-D897-4A61-A7CD-4C0165BD84C9 Clairborne S.  Researcher Highlight – Dr Scott…

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BriteVu Featured in Scientific American

BriteVu Featured in Scientific American

Kirschenbaum S. A new view of the cardiovascular system in 3-D. Scientific American. Blogs. October 30, 2015.  http://blogs.scientificamerican.com/guest-blog/a-new-view-of-the-cardiovascular-system-in-3-d/ This is the first scientific publication where the research of Dr Scott Echols at the U of Utah on bird anatomy is published.  BriteVu is also featured including several pictures that show images created by the novel contrast agent.

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Argentine Black and White Tegu Head perfused with BriteVu

Argentine Black and White Tegu Head perfused with BriteVu

Argentine black and white tegu BriteVu arteriovenogram of the head. Courtesy of Dr Colleen Farmer, Department of Biology, University of Utah. This is a ventral (underside) view of the skull showing all of the blood vessels.  Notice the rich blood supply around the powerful lower jaws (mandibles). The tongue can be seen coursing out of the tip of the snout (and aimed toward the top of the picture).   BriteVu was used in the perfusion process. These are 100 µm CT scan slices.

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Argentine B&W Tegu BriteVu Perfusion of Head

Argentine B&W Tegu BriteVu Perfusion of Head

Argentine black and white tegu BriteVu arteriovenogram of the head. Courtesy of Dr Colleen Farmer, Department of Biology, University of Utah. The vasculature is seen all the way to the tip of the tongue. There are several interesting anatomic features of this animal including a radiating vascular ring inside both nares.  This is a lateral view of the head.

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Rat Kidney BriteVu Perfusion for Research

Rat Kidney BriteVu Perfusion for Research

BriteVu perfused rat kidney CT scanned at 30 µm. Courtesy of the Head Injury and Vessel Biomechanics Lab at the University of Utah. The whole rat was perfused for a brain vasculature study.  However all of the tissues were well infiltrated with BriteVu creating incredible perfusions throughout the body.

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Human arm perfused with BriteVu contrast agent

Human arm perfused with BriteVu contrast agent

A human cadaver arm was perfused using BriteVu high radiodensity contrast agent.  The shoulder to the fingers plus the entire associated vasculature are visible.  The arm was CT scanned at 2 mm.  Courtesy of Dr. Bruce Wainman, Education Program in Anatomy, McMaster University.

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Human hand perfused with BriteVu contrast agent

Human hand perfused with BriteVu contrast agent

A human cadaver wrist and hand was perfused using BriteVu high radiodensity contrast agent.  The distal radius and ulna bones plus the entire hand and vasculature are visible.  The hand was CT scanned at 2 mm.  Courtesy of Dr. Bruce Wainman, Education Program in Anatomy, McMaster University.

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BriteVu Perfused Human Wrist

BriteVu Perfused Human Wrist

A human cadaver wrist and hand was perfused using BriteVu high radiodensity contrast agent.  The distal radius and ulna bones plus the entire hand and vasculature are visible.  The hand was CT scanned at 2 mm.  Courtesy of Dr. Bruce Wainman, Education Program in Anatomy, McMaster University.

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BriteVu Perfused Alligator Kidney SEM

BriteVu Perfused Alligator Kidney SEM

As part of a research project using scanning electron microscopy (SEM), BriteVu perfused alligator kidney was evaluated. Because of an equipment failure, the kidney tissue was not coated (which normally reduces electron charging). We decided to go ahead with the SEM anyways. The end result was that the tissues were overcharged (especially the BriteVu perfused vessels) creating bright spots. These bright spots actually highlight the location of the contrast agent within the tissues.  BriteVu is seen as the ‘bright spots’ in between…

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Rat Eye BriteVu Arteriovenogram

Rat Eye BriteVu Arteriovenogram

Window to the soul.  An arteriovenogram reached the eye of a rat and, combined with micro CT, produced a detailed map of the blood supply to and within the eye.  The central (black) portion represents the iris which is immediately outlined by the blood supply to the iris.  The back half of the eye has been digitally removed to create a clearer picture.  CT scan at 10µm.  Courtesy of the Head Injury and Vessel Biomechanics Lab at the University of…

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Rat Heart Perfused with BriteVu CT Contrast Agent

Rat Heart Perfused with BriteVu CT Contrast Agent

Rat heart perfused with BriteVu contrast agent. As a part of a study at the Head Injury and Vessel Biomechanics Lab at the University of Utah, the whole rat was perfused and individual organs were CT scanned for detailed analysis. The 10 µm CT scan shows individual blood vessels in the heart muscle and on the outside (especially along the coronary groove). By understanding vascular flow, researchers can determine areas of increased and decreased blood supply to different parts of the…

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