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Why is BriteVu the Best Contrast Agent?

Apr 25, 2016/ Comments Off / in FAQ

BriteVu offers several distinct advantages over the competition (terminal research contrast agents): –First BriteVu is easy to prepare (simply mix the dry powder with warmed water, physiologic solutions or phenol) in a stirring hot plate. BriteVu also readily mixes with common water soluble dyes (especially food colorings, fluorescein, etc) creating additional color and special labeling options. Major competitor products must be mixed with specific solvents, reagents or other chemicals to perform properly. –Second, and in stark contrast to the competition,…

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What size needle can properly prepared BriteVu pass through?

May 21, 2015/ Comments Off / in FAQ

Liquid BriteVu can easily pass through a 27 gauge needle.  If cooled below 37o C (98.6o F) or not properly mixed, liquid BriteVu will being to harden or form clumps.  If this occurs, first make sure the total water volume is adequate (adjust for evaporation if needed) and heat the solution to 70-80o C (140-158o F) for at least 1 minute.  Even at low temperatures (40oC) BriteVu will pass through a 30 g needle.  However, higher temperatures (60-80oC) will ease…

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Can BriteVu be used in animals other than mice and rats?

Apr 30, 2015/ Comments Off / in FAQ

Yes, BriteVu can conceivably be used in any animal as long it can be perfused into the vasculature, body cavity or other location. To date, BriteVu has been successfully used in a variety of mammals, birds and reptiles plus human cadavers. While most studies are vascular based, BriteVu has been used to define respiratory spaces (sinuses, bronchial tree, air sacs, etc), intra-articular (joint) margins, intestinal lumens and more  We have plans of using BriteVu in amphibians, fish and invertebrates- stay…

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How is BriteVu dosed for different animals?

Apr 30, 2015/ Comments Off / in FAQ

The dose depends on the system or region being perfused.  For intravascular perfusion and after the blood is flushed with saline, infuse the equivalent of 30-40% volume/weight of BriteVu.  However, these are general guidelines that typically fit small animals less than 1,000 g.  See protocols for additional ideas. For example, perfuse 150-200 cc (or ml) of BriteVu into the vasculature of a 500 gram animal. Other systems, like the respiratory system for example, have very different volumes based on the species. …

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How stable is BriteVu once mixed?

Apr 30, 2015/ Comments Off / in FAQ

As long as properly mixed BriteVu is kept at or above 37o C (98.6o F) on a spinning hot plate, it will remain as a stable liquid.  Heated liquid BriteVu will lose water due to evaporation and may periodically need small amounts of water added.

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What size needle can properly prepared BriteVu pass through?

Apr 30, 2015/ Comments Off / in FAQ

Liquid BriteVu can easily pass through a 27 gauge needle.  If cooled below 37 C (98.6 F) or not properly mixed, liquid BriteVu will being to harden or form clumps.  If this occurs, first make sure the total water volume is adequate (adjust for evaporation if needed) and heat the solution to 80-90 C (140-158 F) for at least 10 minutes.

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Is BriteVu toxic?

Apr 30, 2015/ Comments Off / in FAQ

BriteVu is non-toxic.  Regardless basic precautions should be followed: keep out of the reach of children, avoid contact with eyes and skin and do not eat.  BriteVu should NOT be used on living animals. A Safety Data Sheet can be requested through our contact page.  In  case of suspected intoxication with BriteVu, please contact Infotrac at 1-800-535-5053 (North America) or 1-352-323-3500 (International).

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